Polynucleotides are a regenerative injectable treatment, built from purified DNA fragments. The treatment supports your skin’s own repair and hydration processes, working at a cellular level to reduce inflammation and improve your skin’s ability to hold moisture. At Kirei Clinic, Dr Rosie leads every polynucleotide treatment personally. She was previously a national trainer for polynucleotides.

What Are Polynucleotides?

Polynucleotides come from purified DNA fragments, delivered by injection to support your skin’s repair processes. Unlike dermal filler, polynucleotides add no volume. Instead, they work on skin quality, encouraging tissue repair, calming irritation and improving hydration from within.

Patients turn to polynucleotides for tired, dehydrated or thinning skin, particularly under the eyes, on the neck and décolletage, and across the face. Some patients use the treatment to support scalp and hair quality too. Results build gradually across a short course of sessions, spaced several weeks apart, as your skin’s repair processes respond.

Polynucleotides differ from collagen biostimulators such as Sculptra. Rather than driving heavy new collagen production, polynucleotides focus on repair, hydration and calming fatigued or irritated skin. Many patients combine polynucleotides with other treatments as part of a wider plan, confirmed at consultation. For a broader look at how polynucleotides compare with other skin boosters, including Profhilo, Belotero REVIVE and SKINVIVE, visit our Skin Boosters page.

Why Dr Rosie?

Dr Rosie is a GDC-registered dentist and Newcastle University graduate. Before joining Kirei Clinic, she worked as a national trainer for polynucleotides, teaching the technique to other practitioners across the country. Polynucleotides are her named specialism at Kirei Clinic, and no other clinician here treats patients with this product. Every consultation with Dr Rosie starts with an assessment of your whole face, not one isolated area. Your skin, your bone structure and your movement patterns all inform your plan, since a change in one part of your face affects how the rest reads.

FAQs

What are polynucleotides used for?

Polynucleotides improve skin quality, hydration and repair. Patients use the treatment for tired or thinning skin under the eyes, on the neck and décolletage, and across the face.

No. Dermal filler adds volume using a hyaluronic acid gel. Polynucleotides add no volume. Instead, they support your skin’s own repair and hydration processes.

Most patients need a short course, spaced several weeks apart. Results build gradually across the course, as your skin responds to treatment. Dr Rosie confirms your schedule at consultation.

Dr Rosie leads polynucleotide treatment at Kirei Clinic. She is a GDC-registered dentist and Newcastle University graduate, previously a national trainer for polynucleotides.

Improvement in skin hydration and quality develops over several weeks, building across your course of treatment.

Polynucleotide treatment is not suitable during pregnancy or breastfeeding. Dr Rosie reviews your medical history at consultation to confirm the treatment fits your circumstances.

Available in Leeds

Polynucleotide treatment is available at our Leeds city centre clinic. Kirei Clinic also treats patients at Perfect32 Dental Practice in Beverley, a CQC-registered setting where Dr Mei practises, but polynucleotide treatment stays with Dr Rosie, who practises at Kirei Clinic Leeds only. If dull or dehydrated skin concerns you, read our dedicated page on Dull or Dehydrated Skin for a wider view of your options.

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